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1

Physicochemical Characterization of Creatine N -Methylguanidinium Salts

Gufford, Brandon T., Sriraghavan, Kamaraj, Miller, Nicholas J., Miller, Donald W., Gu, Xiaochen, Vennerstrom, Jonathan L., Robinson, Dennis H.

Journal:

Journal of Dietary Supplements

Year:

2010

Language:

english

File:

PDF, 386 KB

english, 2010

2

Synthesis of 2,5-dihydroxy[carboxy-14C]benzoic acid for electrochemical protein modification

Varghese John, Jonathan L. Vennerstrom, Thomas J. Holmes Jr.

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

1986

Language:

english

File:

PDF, 165 KB

english, 1986

3

Solution equilibria of deferoxamine amides

Peter M. Ihnat, Jonathan L. Vennerstrom, Dennis H. Robinson

Journal:

Journal of Pharmaceutical Sciences

Year:

2002

Language:

english

File:

PDF, 110 KB

english, 2002

4

An Assessment of Drug-Haematin Binding as a Mechanism for Inhibition of Haematin Polymerisation by Quinoline Antimalarials

Arnulf Dorn, Sudha Rani Vippagunta, Hugues Matile, Catherine Jaquet, Jonathan L Vennerstrom, Robert G Ridley

Journal:

Biochemical Pharmacology

Year:

1998

Language:

english

File:

PDF, 432 KB

english, 1998

5

Synthesis of Tetrasubstituted Ozonides by the Griesbaum Coozonolysis Reaction: Diastereoselectivity and Functional Group Transformations by Post-Ozonolysis Reactions

Tang, Yuanqing, Dong, Yuxiang, Karle, Jean M., DiTusa, Charles A., Vennerstrom, Jonathan L.

Journal:

Journal of Organic Chemistry

Year:

2004

Language:

english

File:

PDF, 89 KB

english, 2004

6

pH-Dependent Stability of Creatine Ethyl Ester: Relevance to Oral Absorption

Gufford, Brandon T., Ezell, Edward L., Robinson, Dennis H., Miller, Donald W., Miller, Nicholas J., Gu, Xiaochen, Vennerstrom, Jonathan L.

Journal:

Journal of Dietary Supplements

Year:

2013

Language:

english

File:

PDF, 333 KB

english, 2013

7

Tricyclic Imidazolidin-4-ones by Witkop Oxidation of Tetrahydro-β-carbolines

Leas, Derek A., Dong, Yuxiang, Garrison, Jered C., Wang, Xiaofang, Ezell, Edward L., Stack, Douglas E., Vennerstrom, Jonathan L.

Journal:

Journal of Organic Chemistry

Year:

2020

Language:

english

File:

PDF, 425 KB

english, 2020

8

Synthesis and solution properties of deferoxamine amides

Peter M. Ihnat, Jonathan L. Vennerstrom, Dennis H. Robinson

Journal:

Journal of Pharmaceutical Sciences

Year:

2000

Language:

english

File:

PDF, 202 KB

english, 2000

9

ChemInform Abstract: Dispiro-1,2,4,5-tetraoxanes via Ozonolysis of Cycloalkanone O-Methyl Oximes: A Comparison with the Peroxidation of Cycloalkanones in Acetonitrile—Sulfuric Acid Media.

Yuxiang Dong, Jonathan L. Vennerstrom

Journal:

Year:

1999

File:

PDF, 30 KB

1999

10

ChemInform Abstract: Differentiation Between 1,2,4,5-Tetraoxanes and 1,2,4,5,7,8-Hexaoxonanes Using 1H and 13C NMR Analyses.

Yuxiang Dong, Jonathan L. Vennerstrom

Journal:

Year:

2001

File:

PDF, 32 KB

2001

11

A 3D QSAR Pharmacophore Model and Quantum Chemical Structure—Activity Analysis of Chloroquine(CQ)-Resistance Reversal.

Apurba K. Bhattacharjee, Dennis E. Kyle, Jonathan L. Vennerstrom, Wilbur K. Milhous

Journal:

Year:

2002

File:

PDF, 26 KB

2002

12

Synthesis of 2H-Pyrroles by Treatment of Pyrrolidines with DDQ.

Srinivasa R. Cheruku, Maniyan P. Padmanilayam, Jonathan L. Vennerstrom

Journal:

Year:

2003

File:

PDF, 87 KB

2003

13

Synthetic Peroxides as Antimalarials

Yuanqing Tang, Yuxiang Dong, Jonathan L. Vennerstrom

Journal:

Year:

2004

File:

PDF, 49 KB

2004

14

The Reaction of Carbonyldiimidazole with Alcohols to Form Carbamates and N-Alkylimidazoles.

Yuanqing Tang, Yuxiang Dong, Jonathan L. Vennerstrom

Journal:

Year:

2005

File:

PDF, 22 KB

2005

15

ChemInform Abstract: A One-Pot Synthesis of Unsymmetrical Bis-Styrylbenzenes.

Daniel P. Flaherty, Yuxiang Dong, Jonathan L. Vennerstrom

Journal:

Year:

2010

File:

PDF, 27 KB

2010

16

ChemInform Abstract: The Activity of Dispiro Peroxides Against Fasciola hepatica.

Xiaofang Wang, Qingjie Zhao, Mireille Vargas, Yuxiang Dong, Kamaraj Sriraghavan, Jennifer Keiser, Jonathan L. Vennerstrom

Journal:

Year:

2012

Language:

english

File:

PDF, 40 KB

english, 2012

17

Three-Dimensional Database Mining Identifies a Unique Chemotype that Unites Structurally Diverse Botulinum Neurotoxin Serotype A Inhibitors in a Three-Zone Pharmacophore

Ann R. Hermone, James C. Burnett, Jonathan E. Nuss, Lyal E. Tressler, Tam L. Nguyen, Bogdan A. Šolaja, Jonathan L. Vennerstrom, James J. Schmidt, Peter Wipf, Sina Bavari, Rick Gussio

Journal:

Year:

2008

Language:

english

File:

PDF, 726 KB

english, 2008

18

Differentiation between 1,2,4,5-tetraoxanes and 1,2,4,5,7,8-hexaoxonanes using 1H and 13C NMR analyses

Yuxiang Dong, Jonathan L. Vennerstrom

Journal:

Journal of Heterocyclic Chemistry

Year:

2001

Language:

english

File:

PDF, 38 KB

english, 2001

19

Chemical kinetics and aqueous degradation pathways of a new class of synthetic ozonide antimalarials

Christine S. Perry, Susan A. Charman, Richard J. Prankerd, Francis C.K. Chiu, Yuxiang Dong, Jonathan L. Vennerstrom, William N. Charman

Journal:

Journal of Pharmaceutical Sciences

Year:

2006

Language:

english

File:

PDF, 238 KB

english, 2006

20

Iron-mediated degradation kinetics of substituted dispiro-1,2,4-trioxolane antimalarials

Darren J. Creek, William N. Charman, Francis C.K. Chiu, Richard J. Prankerd, Kevin J. McCullough, Yuxiang Dong, Jonathan L. Vennerstrom, Susan A. Charman

Journal:

Journal of Pharmaceutical Sciences

Year:

2007

Language:

english

File:

PDF, 207 KB

english, 2007

21

Synthetic peroxides as antimalarials

Yuanqing Tang, Yuxiang Dong, Jonathan L. Vennerstrom

Journal:

Medicinal Research Reviews

Year:

2004

Language:

english

File:

PDF, 294 KB

english, 2004

22

Conformational sampling of the botulinum neurotoxin serotype a light chain: implications for inhibitor binding

James C. Burnett, James J. Schmidt, Connor F. McGrath, Tam L. Nguyen, Ann R. Hermone, Rekha G. Panchal, Jonathan L. Vennerstrom, Krishna Kodukula, Daniel W. Zaharevitz, Rick Gussio, Sina Bavari

Journal:

Bioorganic & Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 919 KB

english, 2005

23

Spiroadamantyl 1,2,4-trioxolane, 1,2,4-trioxane, and 1,2,4-trioxepane pairs: Relationship between peroxide bond iron(II) reactivity, heme alkylation efficiency, and antimalarial activity

Xiaofang Wang, Darren J. Creek, Charles E. Schiaffo, Yuxiang Dong, Jacques Chollet, Christian Scheurer, Sergio Wittlin, Susan A. Charman, Patrick H. Dussault, James K. Wood, Jonathan L. Vennerstrom

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 323 KB

english, 2009

24

Praziquantel analogs with activity against juvenile Schistosoma mansoni

Yuxiang Dong, Jacques Chollet, Mireille Vargas, Nuha R. Mansour, Quentin Bickle, Yazen Alnouti, Jiangeng Huang, Jennifer Keiser, Jonathan L. Vennerstrom

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 237 KB

english, 2010

25

The structure and antimalarial activity of dispiro-1,2,4,5-tetraoxanes derived from (+)-dihydrocarvone

Yuxiang Dong, Kevin J. McCullough, Sergio Wittlin, Jacques Chollet, Jonathan L. Vennerstrom

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 266 KB

english, 2010

26

A one-pot synthesis of unsymmetrical bis-styrylbenzenes

Daniel P. Flaherty, Yuxiang Dong, Jonathan L. Vennerstrom

Journal:

Tetrahedron Letters

Year:

2009

Language:

english

File:

PDF, 179 KB

english, 2009

27

Activity of artemether and OZ78 against triclabendazole-resistant Fasciola hepatica

Jennifer Keiser, Jürg Utzinger, Jonathan L. Vennerstrom, Yuxiang Dong, Gerry Brennan, Ian Fairweather

Journal:

Transactions of the Royal Society of Tropical Medicine and Hygiene

Year:

2007

Language:

english

File:

PDF, 169 KB

english, 2007

28

Efficacy, safety and pharmacokinetics of 1,2,4-trioxolane OZ78 against an experimental infection with Fasciola hepatica in sheep

Jennifer Keiser, Carla Kirchhofer, Manuel Haschke, Jörg Huwyler, Yuxiang Dong, Jonathan L. Vennerstrom, Kathleen Vanhoff, Ronald Kaminsky, Nick Malikides

Journal:

Veterinary Parasitology

Year:

2010

Language:

english

File:

PDF, 206 KB

english, 2010

29

Synthesis of 2H-pyrroles by treatment of pyrrolidines with DDQ

Srinivasa R. Cheruku, Maniyan P. Padmanilayam, Jonathan L. Vennerstrom

Journal:

Tetrahedron Letters

Year:

2003

Language:

english

File:

PDF, 106 KB

english, 2003

30

Identification of an antimalarial synthetic trioxolane drug development candidate

Vennerstrom, Jonathan L., Arbe-Barnes, Sarah, Brun, Reto, Charman, Susan A., Chiu, Francis C. K., Chollet, Jacques, Dong, Yuxiang, Dorn, Arnulf, Hunziker, Daniel, Matile, Hugues

Journal:

Year:

2004

Language:

english

File:

PDF, 246 KB

english, 2004

31

Crystal structure of the potent bisquinoline antimalarial agent (±)-trans-N1,N2-bis(7-chloroquinolin-4-yl) cyclohexane-1,2-diamine dimethanesulfonate salt hydrate in relation to its biological properties

Jean M. Karle, Apurba K. Bhattacharjee, Jonathan L. Vennerstrom

Journal:

Journal of Chemical Crystallography

Year:

2002

Language:

english

File:

PDF, 145 KB

english, 2002

32

Systemic and ocular pharmacokinetics of N-4-benzoylaminophenylsulfonylglycine (BAPSG), a novel aldose reductase inhibitor

Gangadhar Sunkara, Surya P. Ayalasomayajula, Cheruku S. Rao, Jonathan L. Vennerstrom, Uday B. Kompella, Jack DeRuiter, Uday B. Kompella

Journal:

Journal of Pharmacy and Pharmacology

Year:

2004

Language:

english

File:

PDF, 281 KB

english, 2004

33

Dispiro-1,2,4,5-tetraoxanes via Ozonolysis of Cycloalkanone O-Methyl Oximes: A Comparison with the Peroxidation of Cycloalkanones in Acetonitrile−Sulfuric Acid Media

Dong, Yuxiang, Vennerstrom, Jonathan L.

Journal:

Journal of Organic Chemistry

Year:

1998

Language:

english

File:

PDF, 78 KB

english, 1998

34

The activity of dispiro peroxides against Fasciola hepatica

Xiaofang Wang, Qingjie Zhao, Mireille Vargas, Yuxiang Dong, Kamaraj Sriraghavan, Jennifer Keiser, Jonathan L. Vennerstrom

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 384 KB

english, 2011

35

Biological evaluation and docking studies of recently identified inhibitors of phosphoinositide-3-kinases

Dima A. Sabbah, Neka A. Simms, Michael G. Brattain, Jonathan L. Vennerstrom, Haizhen Zhong

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 752 KB

english, 2012

36

Oxidative stress in malaria parasite-infected erythrocytes: host–parasite interactions

Katja Becker, Leann Tilley, Jonathan L. Vennerstrom, David Roberts, Stephen Rogerson, Hagai Ginsburg

Journal:

International Journal for Parasitology

Year:

2004

Language:

english

File:

PDF, 794 KB

english, 2004

37

Comparative embryotoxicity of different antimalarial peroxides: In vitro study using the rat whole embryo culture model (WEC)

Monica Longo, Sara Zanoncelli, Marco Brughera, Paolo Colombo, Sergio Wittlin, Jonathan L. Vennerstrom, Joerg Moehrle, J. Carl Craft

Journal:

Reproductive Toxicology

Year:

2010

Language:

english

File:

PDF, 646 KB

english, 2010

38

Deferoxamine: Stimulation of hematin polymerization and antagonism of its inhibition by chloroquine

Sudha R Vippagunta, Arnulf Dorn, André Bubendorf, Robert G Ridley, Jonathan L Vennerstrom

Journal:

Biochemical Pharmacology

Year:

1999

Language:

english

File:

PDF, 397 KB

english, 1999

39

Phenolic Bis-styrylbenzenes as β-Amyloid Binding Ligands and Free Radical Scavengers

Flaherty, Daniel P., Kiyota, Tomomi, Dong, Yuxiang, Ikezu, Tsuneya, Vennerstrom, Jonathan L.

Journal:

Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 2.11 MB

english, 2010

40

Pharmacophore Refinement Guides the Design of Nanomolar-Range Botulinum Neurotoxin Serotype A Light Chain Inhibitors

Nuss, Jonathan E., Dong, Yuxiang, Wanner, Laura M., Ruthel, Gordon, Wipf, Peter, Gussio, Rick, Vennerstrom, Jonathan L., Bavari, Sina, Burnett, James C.

Journal:

ACS Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 2.13 MB

english, 2010

41

Docking Studies on Isoform-Specific Inhibition of Phosphoinositide-3-Kinases

Sabbah, Dima A., Vennerstrom, Jonathan L., Zhong, Haizhen

Journal:

Journal of Chemical Information and Modeling

Year:

2010

Language:

english

File:

PDF, 3.91 MB

english, 2010

42

Electrolysis-mediated irreversible inactivation of lipoxygenase directed toward electroaffinity labelling

Thomas J. Holmes Jr., Jonathan L. Vennerstrom, Varghese John

Journal:

Biochemical and Biophysical Research Communications

Year:

1984

Language:

english

File:

PDF, 390 KB

english, 1984

43

Activity of OZ78 analogues against Fasciola hepatica and Echinostoma caproni

Carla Kirchhofer, Mireille Vargas, Olivier Braissant, Yuxiang Dong, Xiaofang Wang, Jonathan L. Vennerstrom, Jennifer Keiser

Journal:

Year:

2011

Language:

english

File:

PDF, 730 KB

english, 2011

44

Novel small molecule inhibitors of botulinum neurotoxin A metalloprotease activity

James C Burnett, James J Schmidt, Robert G Stafford, Rekha G Panchal, Tam L Nguyen, Ann R Hermone, Jonathan L Vennerstrom, Connor F McGrath, Douglas J Lane, Edward A Sausville, Daniel W Zaharevitz, Ri

Journal:

Biochemical and Biophysical Research Communications

Year:

2003

Language:

english

File:

PDF, 383 KB

english, 2003

45

Characterization of chloroquine-hematin μ-oxo dimer binding by isothermal titration calorimetry

Sudha Rani Vippagunta, Arnulf Dorn, Robert G. Ridley, Jonathan L. Vennerstrom

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

2000

Language:

english

File:

PDF, 247 KB

english, 2000

46

Immunization to nicotine with a peptide-based vaccine composed of a conformationally biased agonist of C5a as a molecular adjuvant

Sam D Sanderson, Srinivasa R Cheruku, Maniyan P Padmanilayam, Jonathan L Vennerstrom, Geoffrey M Thiele, Matthew I Palmatier, Rick A Bevins

Journal:

International Immunopharmacology

Year:

2003

Language:

english

File:

PDF, 201 KB

english, 2003

47

Prostaglandin-H synthase inhibition by malonamides. Ring-opened analogs of phenylbutazone

Vennerstrom, Jonathan L., Holmes, Thomas J.

Journal:

Journal of Medicinal Chemistry

Year:

1987

Language:

english

File:

PDF, 541 KB

english, 1987

48

Binding Selectivity Studies of Phosphoinositide 3-Kinases Using Free Energy Calculations

Sabbah, Dima A., Vennerstrom, Jonathan L., Zhong, Haizhen A.

Journal:

Journal of Chemical Information and Modeling

Year:

2012

Language:

english

File:

PDF, 1.64 MB

english, 2012

49

N-Phenyl-4-hydroxy-2-quinolone-3-carboxamides as selective inhibitors of mutant H1047R phosphoinositide-3-kinase (PI3Kα)

Dima A. Sabbah, Neka A. Simms, Wang Wang, Yuxiang Dong, Edward L. Ezell, Michael G. Brattain, Jonathan L. Vennerstrom, Haizhen A. Zhong

Journal:

Bioorganic & Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 1.10 MB

english, 2012

50

A Comparison and Analysis of Several Ways to Promote Haematin (Haem) Polymerisation and an Assessment of Its Initiation In Vitro

Arnulf Dorn, Sudha Rani Vippagunta, Hugues Matile, André Bubendorf, Jonathan L. Vennerstrom, Robert G. Ridley

Journal:

Biochemical Pharmacology

Year:

1998

Language:

english

File:

PDF, 610 KB

english, 1998